I hear a squeak when you start the game

Fans and coolers can't squeak and whistle, they either make noise, hum and/or vibration, or do not work. Squeak (or whistle in this case are one and the same) inductors or capacitors, which are in the power supply, the motherboard, and can be on the graphics card. Need to identify the source of the whistle. If the whistle goes at the rear of the system unit, then this power supply. If a whistle is heard from below, the video card or motherboard. The inductor looks like a coil with the yellow-orange of the copper wires, the capacitor looks like a small cylinder with a cross tip. The choke whistles under heavy load, in your case with the game. If whistles capacitor, it means that he will soon fail, requiring replacement. But in most cases, blame the throttle. Whistling is not to say that it's good, but it could Herald a quick breakdown of the containing device (this is more about the power supply), or its low quality, especially if whistles constantly. This is the case from my experiences, when I self-identified the fault in your power supply, to prevent the combustion components of your PC. My power supply was whistling because I didn't clean it for 8 years, then clean it later - it broke because of the huge amounts of dust and, consequently, against overheating. Generally, in this situation, you can relax for now, but if you will whistle constantly, then change the source of the whistle/squeak on other more qualitative or bring it to service.

Probably it chokes on the graphics card. The higher the FPS, the more intense the whistle.