There was a problem with the console (The Binding of Isaac)

There was a problem with the console. Yes, I confess I play with a pirate and I really want to close the twins (how my ass burns with them). so everyone writes that the console is activated through the options file, which is in my games folder. I changed the parameter needed to turn on the console - and nothing. restarted the game, the computer is also the result of zero.