Screen flickering (Cities: Skylines)

Good evening. The people tell me.
Downloaded the game installed it but for some reason when you enter the game the screen flickers in the game is the land of the river, the panel is normally displayed. What could be the problem? is it possible to solve?

CPU: Intel core 2 Quad CPU Q8300 2.5 Hz
RAM: 5g
Graphics: GS 250 1гиг