I can't save. Last autosave was an hour ago (Red Dead Redemption 2)

Gleb Denisenko
cannot help about the settings, because I had no problems with them, but I could not save only if there were enemies nearby. Moreover, they were not even always shown on the map. In general, I just moved away from the original place, and the opportunity to save appeared. Well, you can also try to die in the game, because after death you appear in a safe place, it can work.
Although personally, I have such problems very rarely.

Gleb Denisenko
Set up your tent and save yourself.