Fallout 4 crash due to NMM manager

I go to Fallout 4 through NMM and after a few minutes or an hour of the game it crashes, usually there are no errors after the crash. I tried to reinstall it (it does not help), what this may be due to I don’t understand, the computer quietly pulls Fallout at medium high settings (Mods do not affect performance, since I turned them off completely. It crashes because of launching through NMM). Please advise me what to do so that this mistake does not happen again.
(I will be very grateful)
PS. Vortex is also bullshit.